Epidemiology and clinical characteristics of colorectal cancer and advanced adenoma: a single center experience in Jordan
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View abstract on PubMed
Summary
This summary is machine-generated.Colorectal polyps are prevalent in Jordan, affecting 28.1% of patients. Risk factors include older age, high BMI, male gender, and certain health conditions, highlighting the need for targeted screening for colorectal cancer (CRC).
Area Of Science
- Gastroenterology
- Epidemiology
- Oncology
Background
- Colorectal polyps are precursors to colorectal cancer (CRC).
- Understanding the epidemiology and clinical characteristics of colorectal polyps is crucial for developing effective screening programs.
Purpose Of The Study
- To evaluate the epidemiology and clinical characteristics of colorectal polyps.
- To identify predictors of colorectal polyps in a Jordanian cohort.
- To inform the formulation of an appropriate screening program for colorectal cancer.
Main Methods
- Retrospective chart review of 965 patients undergoing colonoscopy at Jordan University Hospital (January-September 2018).
- Evaluation of demographics, comorbidities, lifestyle, medical history, and polyp characteristics.
- Binary logistic regression analysis to identify predictors of colorectal polyps.
Main Results
- Colorectal polyps were detected in 28.1% of patients.
- Positive predictors for polyps included older age, high BMI, male gender, diabetes, dyslipidemia, ischemic heart disease, and family history of CRC.
- The most common polyp location was the right colon (51%), and the most common histologic subtype was tubular adenoma (48.2%).
- The prevalence of colorectal cancer (CRC) was 18.65 per 1000 patients.
Conclusions
- Colorectal polyps and CRC are notably prevalent in the Jordanian population.
- Awareness campaigns, targeted screening, and promotion of healthy lifestyles are recommended to reduce the disease burden, especially in high-risk individuals.
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