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Updated: May 25, 2025

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Microdialysis of Ethanol During Operant Ethanol Self-administration and Ethanol Determination by Gas Chromatography
Published on: September 5, 2012
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[Method of linear calibration function control according to GOST R ISO 11095-2007 for measuring the mass
M S Zatyamina1,2,3, L A Smirnova1,2, O V Ostrovskij1
1Volgograd State Medical University, Volgograd, Russia.
Sudebno-Meditsinskaia Ekspertiza
|February 28, 2025
Summary
Calibration functions were validated using a control method with standard and internal reference materials (RMs). The system remained in a controlled state, confirming the calibration function
Area of Science:
- Analytical Chemistry
- Metrology
Context:
- Calibration functions require regular validation to ensure accuracy.
- GOST R ISO 11095-2007 provides a framework for method validation.
- Reference Materials (RMs) are crucial for quality control in analytical measurements.
Purpose:
- To implement a control method for validating existing calibration functions.
- To assess the stability and reliability of calibration functions using both standard and internal RMs.
- To ensure compliance with GOST R ISO 11095-2007 standards.
Summary:
- A control method was applied to validate calibration functions for aqueous ethanol solutions.
- Standard RMs and internally developed RMs were used for validation.
- Control charts demonstrated that the system was in a controlled state, requiring no updates to the calibration function.
- Uncertainty assessment was performed during the validation process.
Impact:
- Confirms the long-term stability of calibration functions.
- Ensures the reliability of analytical measurements for ethanol concentration.
- Provides a robust framework for ongoing quality assurance in chemical analysis.
Keywords:
GOST R ISO 11095-2007comparison sampleconcentrationcontrol chartcontrol methodethanoluncertaintyMore Related Videos
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