Related Experiment Video
Updated: May 25, 2025

Surgical Retrieval, Isolation and In vitro Expansion of Human Anterior Cruciate Ligament-derived Cells for Tissue Engineering Applications
Published on: April 30, 2014
All-inside single-bundle and modified double-bundle anterior cruciate ligament reconstruction techniques guarantee
Moretti Lorenzo1, Garofalo Raffaele2, Cassano Giuseppe Danilo2
1Department of Translational Biomedicine and Neuroscience (DiBraiN), Orthopaedic and Trauma Unit, AOUC Policlinico di Bari University of Bari "Aldo Moro" Bari Italy.
Purpose:
The aim of the present study was to compare clinical and radiological outcomes between the all-inside single bundle (SB) and a modified double-bundle (DB) anterior cruciate ligament reconstructions (ACLR) at over 5-year follow-up.
Methods:
This is an observational, retrospective comparative, two-centre study. Clinical outcomes were evaluated using Lysholm and International Knee Documentation Committee (IKDC) scores, and anterior tibial translation (ATT) was assessed using the KT-1000 arthrometer. Knee x-ray images were recorded, classified according to the KL grading and compared with radiographs of the same patient before surgery. Inclusion criteria were patients undergoing ACLR, age between 18 and 45 years and negative knee history of major traumatic events after surgery. Exclusion criteria were congenital laxity, combined multiple knee ligament injuries, patients undergoing ACL revision surgery, history of infection, lower limb coronal axial deviation >5°, patients undergoing lateral extra-articular tenodesis or anterolateral ligament reconstruction, patients with chondral damage Outerbridge grade >2, patients with meniscal tears undergoing subtotal meniscectomy or meniscal repair and patients with knee OA Kellgren-Lawrance (KL) grade >3.
Results:
One hundred and fifty-two patients were included in the study. Patients were divided into two groups according to surgical technique: Group A-ACLR with all-inside technique, and Group B-ACLR with modified DB technique. There were no statistical differences between groups for age, side, gender or time since surgery.There were no statistically significant differences between groups for Lysholm scores (p = 0.43), IKDC (p = 0.88), ATT (p = 0.105) and KL grade (p = 0.93 before surgery, 0.99 at the fu). KL grade increased significantly since pre-op.
Conclusions:
Our data show significant improvements in all clinical outcome measures, along with excellent KT-1000 arthrometer values and low clinical failure rates for both the SB all-inside and modified DB techniques at a mean follow-up of over 6 years. There were no significant differences in arthritic progression according to KL grade between groups.
Level Of Evidence:
Level III.
More Related Videos
05:07Author Spotlight: Implementing the Enhanced Recovery After Surgery Concept in Rehabilitation Following Anterior Cruciate Ligament Reconstruction
Published on: March 1, 2024
05:44Author Spotlight: Double Posteromedial Approach for Treating Posterior Cruciate Ligament Cysts
Published on: October 20, 2023