Unveiling the pathways: identifying the multifaceted determinants of low birth weight among neonates in low-income

Angefa Ayele1, Dukele Boneya1, Dube Jara1,2

  • 1Department of Epidemiology, School of Public Health, Institute of Health, Bule Hora University, Bule Hora, Ethiopia.

BMJ Public Health
|February 28, 2025
PubMed

Insights

Low birth weight is linked to maternal factors like poor nutrition and anemia. Early antenatal care and nutritional support are key to reducing low birth weight in newborns.

Area of Science:

  • Public Health
  • Neonatal Health
  • Maternal Health

Background:

  • Low birth weight (LBW), defined as <2500g, is a global public health issue with significant short- and long-term consequences.
  • Identifying risk factors for LBW is crucial for targeted interventions and improving neonatal outcomes.
  • This study investigates the determinants of LBW in neonates born in public hospitals in Southern Ethiopia.

Purpose of the Study:

  • To determine the common risk factors associated with low birth weight among neonates in Southern Ethiopia.
  • To provide evidence for public health strategies aimed at reducing the incidence of LBW.

Main Methods:

  • An unmatched case-control study involving 258 neonates (86 cases, 172 controls) was conducted.
  • Data were collected from public hospitals between April 15 and May 25, 2022, using consecutive and systematic sampling.
  • Multivariable logistic regression analysis was employed to identify significant determinants (p<0.05).

Main Results:

  • Key determinants of LBW included lack of iron/folic acid supplementation (AOR 2.47), inadequate meal intake (AOR 2.66), anemia (AOR 3.45), and pregnancy-induced hypertension (AOR 2.49).
  • Low mid-upper arm circumference (MUAC) (AOR 6.74), late gestational age at first antenatal care (ANC) visit (≥24 weeks, AOR 7.31), and minimum food diversity (AOR 4.2) were also significant risk factors.
  • These factors collectively contribute to the increased odds of neonates being born with low birth weight.

Conclusions:

  • Maternal nutritional status (iron/folic acid, meal intake, food diversity), anemia, pregnancy-induced hypertension, and timely initiation of ANC are critical factors influencing birth weight.
  • Interventions focusing on improving maternal nutrition, managing anemia and hypertension, and promoting early ANC attendance are recommended to reduce LBW rates.
  • Further evaluation of risk factors and comprehensive maternal care are essential for effective LBW prevention strategies.
Abstract

Related Concept Videos

Nature and Nurture01:10

Nature and Nurture

Many human characteristics, like height, are shaped by both nature—in other words, by our genes—and by nurture, or our environment. For example, chronic stress during childhood inhibits the production of growth hormones and consequently reduces bone growth and height. Scientists estimate that 70-90% of variation in height is due to genetic differences among individuals, and 10-30% of variation in height is due to differences in the environments that individuals experience,...
20.3K
Regression Toward the Mean01:52

Regression Toward the Mean

Regression toward the mean (“RTM”) is a phenomenon in which extremely high or low values—for example, and individual’s blood pressure at a particular moment—appear closer to a group’s average upon remeasuring. Although this statistical peculiarity is the result of random error and chance, it has been problematic across various medical, scientific, financial and psychological applications. In particular, RTM, if not taken into account, can interfere when...
6.3K
Anatomy of the Intestines01:23

Anatomy of the Intestines

Although digestion of proteins, carbohydrates, and lipids may begin in the stomach, it is completed in the intestine. The absorption of nutrients, water, and electrolytes from food and drink also occurs in the intestine. The intestines can be divided into two structurally distinct organs—the small and large intestines.
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
71.2K
Environmental Influences on Intelligence01:29

Environmental Influences on Intelligence

Despite the strong genetic influence on traits like intelligence, environmental factors significantly shape outcomes. For example, while over 90% of height variation is due to genetic differences, environmental factors such as nutrition also have a notable impact. Similarly, for intelligence, changes in a child's surroundings can significantly alter their IQ. Research shows that enriched environments boost children's academic success and help them develop key cognitive skills. Children...
172
Teratogenicity01:07

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
2.3K
Factors Affecting Illness01:18

Factors Affecting Illness

When a person's physical, emotional, intellectual, social development or spiritual functioning is compromised, this deviation from a healthy normal state is called illness. Illness creates stress that in turn harms individuals. Irritation, anger, denial, hopelessness, and fear are behavioral and emotional changes an individual experiences in the phases of illness. A variety of factors influence a person's health and well-being.
For instance, risk factors are connected to illness,...
4.1K