Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Acute Pancreatitis II: Clinical Manifestations and Management01:30

Acute Pancreatitis II: Clinical Manifestations and Management

79
Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
79
Acute Pancreatitis I: Introduction01:27

Acute Pancreatitis I: Introduction

314
Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
314
Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

61
The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
61
Chronic Pancreatitis II: Collaborative Care01:29

Chronic Pancreatitis II: Collaborative Care

56
The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
56

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Efficient in vivo cytosine base editing using virus-like particles with uracil DNA glycosylase inhibition.

Nature biotechnology·2026
Same author

Cholecystectomy vs Endoscopic Retrograde Cholangiopancreatography or No Intervention After Gallstone-Related Acute Pancreatitis.

JAMA surgery·2026
Same author

The Farooq, not the Lerner, grading system predicts disease-specific and overall survival in duodenal graft-versus-host disease.

Human pathology·2026
Same author

Liquorice alters adipocyte-breast cancer cell crosstalk by modulating oxidative stress and suppressing aromatase and renin-angiotensin signalling.

International journal of food sciences and nutrition·2026
Same author

The Influence of Lifestyle on Cognitive Function and Quality of Life in People with Dementia.

Neuropsychiatric disease and treatment·2026
Same author

Clinical application of base editing for treating β-thalassaemia.

Nature·2026

Related Experiment Video

Updated: May 24, 2025

Preparing a Mice Model of Severe Acute Pancreatitis via a Combination of Caerulein and Lipopolysaccharide Intraperitoneal Injection
07:38

Preparing a Mice Model of Severe Acute Pancreatitis via a Combination of Caerulein and Lipopolysaccharide Intraperitoneal Injection

Published on: May 10, 2024

424

Long-Term Mortality in Acute Pancreatitis-A Population-Based Cohort Study.

Daniel Selin1,2, John Maret-Ouda2,3, Viktor Oskarsson4,5

  • 1Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.

United European Gastroenterology Journal
|February 28, 2025
PubMed
Summary

Acute pancreatitis significantly increases long-term mortality risk, even when accounting for other health issues and recurrent conditions. This finding highlights the critical need for better understanding and prevention strategies for this pancreatic inflammation.

Keywords:
acute pancreatitischronic pancreatitisepidemiologygall stone pancreatitismortalitypopulation‐based

More Related Videos

Author Spotlight: Advancements in Retroperitoneal Approach for Necrotizing Pancreatitis
03:42

Author Spotlight: Advancements in Retroperitoneal Approach for Necrotizing Pancreatitis

Published on: March 15, 2024

391
Surgical Tips and Tricks for Performing Porcine Pancreas Transplantation
10:32

Surgical Tips and Tricks for Performing Porcine Pancreas Transplantation

Published on: July 20, 2022

1.7K

Related Experiment Videos

Last Updated: May 24, 2025

Preparing a Mice Model of Severe Acute Pancreatitis via a Combination of Caerulein and Lipopolysaccharide Intraperitoneal Injection
07:38

Preparing a Mice Model of Severe Acute Pancreatitis via a Combination of Caerulein and Lipopolysaccharide Intraperitoneal Injection

Published on: May 10, 2024

424
Author Spotlight: Advancements in Retroperitoneal Approach for Necrotizing Pancreatitis
03:42

Author Spotlight: Advancements in Retroperitoneal Approach for Necrotizing Pancreatitis

Published on: March 15, 2024

391
Surgical Tips and Tricks for Performing Porcine Pancreas Transplantation
10:32

Surgical Tips and Tricks for Performing Porcine Pancreas Transplantation

Published on: July 20, 2022

1.7K

Area of Science:

  • Gastroenterology and Hepatology
  • Epidemiology
  • Public Health

Background:

  • Acute pancreatitis, a severe pancreatic inflammation, has a growing incidence globally.
  • Previous research suggests a link between acute pancreatitis and elevated long-term mortality.
  • The influence of chronic pancreatitis or comorbidities like cancer on this association requires further investigation.

Purpose of the Study:

  • To determine the association between acute pancreatitis and long-term all-cause mortality.
  • To analyze mortality risks in acute pancreatitis survivors compared to a general population cohort.

Main Methods:

  • Utilized the Swedish Pancreatitis Cohort (SwePan) database, including first-time acute pancreatitis cases (1990-2019) and matched controls.
  • Employed multivariable conditional Cox proportional hazard models for comparative mortality analysis.
  • Followed 89,465 acute pancreatitis patients and 890,837 controls for over 10 million person-years.

Main Results:

  • Individuals with acute pancreatitis experienced significantly higher all-cause mortality (37.7%) versus controls (29.8%).
  • Increased mortality persisted throughout the follow-up period, especially in severe and non-gallstone cases.
  • The association remained significant even after adjusting for comorbidities and censoring for recurrent or chronic pancreatitis.

Conclusions:

  • Acute pancreatitis is independently linked to increased long-term mortality, irrespective of comorbidities or progression to chronic pancreatitis.
  • Further research is needed to identify specific causes of death and long-term morbidity.
  • Developing tailored follow-up strategies is crucial for the prevention of mortality in acute pancreatitis patients.