Related Experiment Video
Updated: May 24, 2025

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
Published on: September 5, 2017
Tuberculosis infection in patients with rheumatic diseases under different treatments
Tianhui Liu1, Hongxuan Yan1, Mengqiu Gao2
1Beijing Chest Hospital, Capital Medical University/Beijing Tuberculosis and Thoracic Tumor Research Institute, Postal No 9, Beiguan Street, Tongzhou District, Beijing 101149, People's Republic of China.
Objective:
To describe the clinical characteristics of the patients with rheumatic disease who develop tuberculosis(TB), this study investigated the clinical characteristics of patients with rheumatic diseases under different treatments.
Method:
We collected clinical data of patients diagnosed with rheumatic diseases complicated with TB at our hospital from January 2009 to October 2022. The patients were divided into three groups based on medication treatments: the biologic Disease Modifying anti-rheumatic drugs(bDMARDs) group, the no-immunotherapy group, and the conventional Synthetic Disease-Modifying Anti-Rheumatic Drugs (csDMARDs) group. A retrospective analysis was conducted on these three groups.
Results:
We found that patients using bDMARDs were less likely to develop cavities than the other two groups but were more likely to have extrapulmonary tuberculosis(EPTB). Additionally, the majority of patients experienced a time interval of 6 months or less from starting bDMARDs to the diagnosis of TB. The clinical characteristics of TB infection in patients with rheumatic diseases vary under different treatments.
Discussion:
Patients with rheumatic diseases exhibit distinct clinical characteristics under various treatment regimens, such as differences in the presentation and severity of TB infection.
More Related Videos
Related Concept Videos
Pulmonary Tuberculosis V
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
Pulmonary Tuberculosis I
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pulmonary Tuberculosis IV
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Pulmonary Tuberculosis III
The first classification is based on the development of the disease, and it includes the following categories:
Pulmonary Tuberculosis II
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Other Pulmonary Disorders

