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Real-World Impact of Mavacamten on Diastolic Function in Hypertrophic Cardiomyopathy: Insights Beyond Gradient

Roopa A Rao1, Mithilesh K Das1

  • 1Division of Cardiovascular Medicine, Indiana University Health, Indianapolis, Indiana.

The American Journal of Cardiology
|February 28, 2025
PubMed
Abstract

No abstract available in PubMed .

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The activation of the sympathetic nervous system and the renin-angiotensin-aldosterone system (RAAS) contributes to cardiac remodeling, and inhibiting the RAAS is a pharmacological target in heart failure management. As a result, neurohumoral modulation is a crucial treatment principle for managing heart failure. This approach involves using medications like ACE inhibitors (ACEIs), angiotensin receptor blockers (ARBs), β-blockers, mineralocorticoid receptor antagonists (MRAs), and neutral...
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