[Protein metabolism in patients with duodenal ulcers and mathematical modeling of its disorders]

The amino acid composition of blood serum was studied in patients with duodenal ulcers, with this parameter characterizing protein metabolism most delicately. Essential changes were established in the amino acid composition as dependent on a number of factors: disease standing, complications and their duration, acid-forming function of the stomach. Based on the mechanism established, a mathematical model was simulated of protein metabolism impairment associated with peptic ulcer. The use of the model permits making an early diagnosis and correction of the abnormalities described.