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Updated: May 24, 2025

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Admixture as a source for HLA variation in Neolithic European farming communities.

Nicolas Antonio da Silva1, Onur Özer1,2, Magdalena Haller-Caskie1

  • 1Institute of Clinical Molecular Biology, Kiel University, Kiel, Germany.

Genome Biology
|February 28, 2025
PubMed
Summary

Neolithic farmers in northern Europe experienced admixture with hunter-gatherers, altering their immune-relevant human leukocyte antigen (HLA) diversity. This study reveals shifts in HLA alleles and increased diversity in late farmers compared to early farmers.

Keywords:
AdmixtureAncient DNAEuropean NeolithicHLA diversityImmune genesPopulation genetics

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