Navigating Electrocardiographic Risk Stratification and Therapeutic Strategies in Acute Coronary Syndrome Without
1Department of Cardiology, Limassol General Hospital, Limassol, Cyprus; Department of Basic and Clinical Sciences, University of Nicosia Medical School, Nicosia, Cyprus.
Insights
The de Winter ECG pattern, a STEMI equivalent, indicates acute LAD occlusion. Prompt PCI is crucial for patients presenting with this pattern to prevent myocardial infarction.
Area of Science:
- Cardiology
- Electrocardiography
- Medical Diagnostics
Background:
- Acute proximal left anterior descending (LAD) artery occlusion can present with atypical electrocardiographic (ECG) findings.
- The de Winter pattern, characterized by junctional upsloping ST-segment depression and tall, symmetrical T waves, is a recognized but less common manifestation.
- This pattern signifies a high risk of transmural infarction if not treated promptly.
Purpose of the Study:
- To highlight the significance of the de Winter ECG pattern as a STEMI equivalent.
- To present a case of proximal LAD in-stent occlusion manifesting the de Winter pattern.
- To discuss the diagnostic and therapeutic implications of this ECG finding.
Main Methods:
- Case report of a patient with acute proximal LAD occlusion and de Winter ECG pattern.
- Review of the literature concerning the de Winter ECG pattern and ST-segment depression morphology.
- Discussion of the pathophysiology and management strategies for this condition.
Main Results:
- The presented patient with LAD in-stent occlusion showed the de Winter ECG pattern.
- Successful emergency percutaneous coronary intervention (PCI) was performed.
- The patient achieved a good outcome following prompt recognition and management.
Conclusions:
- The de Winter ECG pattern should be recognized as a STEMI equivalent requiring urgent management.
- Prompt PCI is essential for patients with the de Winter pattern to prevent significant myocardial infarction.
- Understanding ECG morphology in acute coronary syndromes aids in risk stratification and therapeutic decision-making.
Abstract:
Of the patients suffering acute proximal left anterior descending (LAD) artery occlusion, a small but not insignificant minority does not manifest the classical ST-segment elevation myocardial infarction (STEMI) electrocardiographic (ECG) patterns. They manifest junctional upsloping ST-segment depression followed by tall, symmetrical T waves in the precordial leads instead, known as the de Winter pattern. Such patients may suffer a nearly transmural infarct if not managed promptly with percutaneous coronary intervention (PCI). Therefore, they should be treated as suffering a STEMI equivalent. The patient presented here suffered a total proximal "wrap-around" LAD artery in-stent occlusion manifesting the de Winter ECG pattern. The latter, was correctly and promptly recognized and the patient was managed successfully with emergency PCI achieving a good outcome. Discussion pertains to the morphology of ST-segment depression (STD) and the polarity and magnitude of the T waves accompanying STD which provide prognostic information and facilitate risk stratification in patients presenting with non-ST-segment elevation acute coronary syndrome. The pathophysiology underlying the de Winter ECG pattern and the appropriate therapeutic strategy are also discussed. The Littmann concept is also discussed, providing a reliable explanation for the ST-segment elevation observed in a misplaced lead V1.
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