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Updated: May 24, 2025

A Guide to Production, Crystallization, and Structure Determination of Human IKK1/α
11:27

A Guide to Production, Crystallization, and Structure Determination of Human IKK1/α

Published on: November 2, 2018

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IKAROS protein stability is regulated by its early N-terminal region and C-terminal dimerization domain

Natchanun Klangkalya1, Ana Esteve-Sole2, Agustin A Gil Silva2

  • 1Immunology Service, Department of Laboratory Medicine, NIH Clinical Center, NIH, Bethesda, MD, USA; Department of Pediatric, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

Clinical Immunology (Orlando, Fla.)
|March 2, 2025
PubMed

Keywords:
HaploinsufficiencyIKZF1Inborn errors of immunityPrimary immunodeficiencyProtein stabilityTranscription factors

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