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Sleep Disorders in CKD: A Review.

Anjana Gopal1, Janine Farragher2, Sarbjit V Jassal3

  • 1Ajmera Transplant Centre, University Health Network and Division of Nephrology, University of Toronto, Toronto, Ontario, Canada.

American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation
|March 2, 2025
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Summary
This summary is machine-generated.

Sleep disorders like insomnia and sleep apnea are common in chronic kidney disease (CKD) but often missed. Addressing these sleep issues in CKD patients may improve quality of life.

Keywords:
Chronic kidney diseasequality of lifesleep disorders

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Area of Science:

  • Nephrology
  • Sleep Medicine
  • Internal Medicine

Background:

  • Sleep disorders are frequent in chronic kidney disease (CKD) patients, contributing to high morbidity and mortality.
  • Common disturbances include insomnia, sleep apnea, restless legs syndrome, and periodic limb movement disorder.
  • CKD symptoms often overlap with sleep disorder symptoms, complicating diagnosis.

Purpose of the Study:

  • To review the pathophysiology, diagnosis, and treatment of sleep disorders in CKD patients.
  • To highlight the challenges in managing these conditions due to overlapping symptoms and treatment complexities.
  • To emphasize the potential benefits of treating sleep disorders in CKD.

Main Methods:

  • Literature review focusing on pathophysiology, diagnosis, and treatment strategies.
  • Analysis of the interplay between CKD and sleep disturbances.
  • Discussion of individualized treatment approaches.

Main Results:

  • Sleep disorders are underrecognized in CKD, exacerbating patient outcomes.
  • Diagnosis is challenging due to symptom overlap.
  • Treatment requires careful individualization to manage potential adverse effects.

Conclusions:

  • Effective management of sleep disorders in CKD is crucial.
  • Individualized treatment strategies can improve patient quality of life.
  • Further research and clinical attention are needed for this patient population.