Related Experiment Video
Updated: May 24, 2025

Author Spotlight: Traditional Chinese Medicine for Sleep Disorders in Acute COPD — A Safe, Cost-Effective Approach
Published on: October 18, 2024
Sleep Disorders in CKD: A Review
Anjana Gopal1, Janine Farragher2, Sarbjit V Jassal3
1Ajmera Transplant Centre, University Health Network and Division of Nephrology, University of Toronto, Toronto, Ontario, Canada.
Abstract:
Sleep disorders are highly prevalent in patients with chronic kidney disease (CKD) but are often underrecognized. The most common sleep disturbances in people with CKD include insomnia, sleep apnea syndrome, restless legs syndrome, and periodic limb movement disorder. The presence of sleep disorders in CKD can further worsen the burden of high morbidity and mortality in a patient population with already high mortality rates. The detection and management of sleep disorders in patients with CKD are often challenging because the classic symptoms of sleep disorders (poor concentration, daytime sleepiness, and insomnia) overlap with CKD symptomatology. The treatment of one symptom may have a negative impact on others; hence treatment of these disorders is challenging and may need to be individualized and modified based on the response to treatment and the development of adverse effects. However, treatment of sleep disorders may have significant clinical benefits, leading to improved health-related quality of life. This Review presents an overview of sleep disorders in patients with CKD, with emphasis on relevant pathophysiology, diagnosis and treatment strategies.
More Related Videos
Related Concept Videos
Restless Leg Syndrome and Night Terrors
The exact cause of RLS is not fully understood, but it is believed to involve dopamine, a neurotransmitter that helps regulate muscle movement. Imbalances in dopamine levels...
Nephrons
Narcolepsy
Hormonal Regulation
Factors Affecting Renal Clearance: Renal Impairment
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
REM Sleep Behavior Disorder
RBD is significantly associated with...

