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Concurrent Large-vessel Vasculitis and Small-vessel Vasculitis Accompanied by Basal Cell Carcinoma
Takashi Nawata1, Takayuki Okimura1, Toru Ariyoshi2
1Department of Medicine and Clinical Science, Yamaguchi University Graduate School of Medicine, Japan.
Internal Medicine (Tokyo, Japan)
|March 2, 2025
Summary
This case report highlights paraneoplastic variable vessel vasculitis in a Japanese woman with basal cell carcinoma. It emphasizes considering cancer complications in vasculitis and evaluating vessels in paraneoplastic vasculitis.
Area of Science:
- Rheumatology
- Oncology
- Dermatology
Background:
- Variable vessel vasculitis is a rare systemic vasculitis.
- Paraneoplastic syndromes can manifest with vasculitis.
- Basal cell carcinoma is a common skin cancer.
Purpose of the Study:
- To report a case of variable vessel vasculitis associated with basal cell carcinoma.
- To discuss the potential paraneoplastic nature of this vasculitis presentation.
- To highlight clinical considerations for managing such cases.
Main Methods:
- Case report of a Japanese woman.
- Clinical observation and diagnosis of large- and small-vessel vasculitis.
- Association with concurrent basal cell carcinoma.
Main Results:
- The patient presented with both large- and small-vessel vasculitis.
- The clinical course suggested a paraneoplastic vasculitis.
- Basal cell carcinoma was identified as a concurrent condition.
Conclusions:
- Clinicians should consider cancer as a potential complication in variable vessel vasculitis.
- Evaluation of variable vessels is crucial in managing paraneoplastic vasculitis.
- This case underscores the importance of an interdisciplinary approach.

