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Published on: December 8, 2014
A case of relapsed pan-colonic ulcerative colitis accompanied with gastroduodenal lesions immediately after COVID-19
Katsuya Endo1, Tomonori Satoh2, Yuki Yoshino2
1Division of Gastroenterology, Tohoku Medical and Pharmaceutical University School of Medicine, 1-15-1 Fukumuro, Miyagino-ku, Sendai, Miyagi, 983-8536, Japan. kendo@tohoku-mpu.ac.jp.
Abstract:
Some patients with ulcerative colitis (UC) suffer from complicated UC-associated upper gastrointestinal lesions. However, the trigger of these lesions has not been clarified. Herein, we present a 28-year-old man with relapsed pan-colonic UC accompanied by gastroduodenal lesions immediately after contracting coronavirus disease 2019 (COVID-19). In this patient, UC relapsed approximately 7 days after the COVID-19 onset, despite being in remission for 3 years. The patient also developed symptoms such as epigastric pain and nausea on day 19 of COVID-19. The endoscopic and pathologic findings of the stomach and duodenum closely resembled colorectal lesions of UC; accordingly, we diagnosed the patient with UC-associated gastroduodenal lesions. Corticosteroids were significantly effective in the colorectal and upper gastrointestinal lesions, leading to remission. This report is the first to describe UC-associated upper GI lesions that developed right after COVID-19 infection. Therefore, COVID-19 can be a possible trigger of UC-associated upper gastrointestinal lesion. Further studies are needed to understand the relationship between the onset of UC or UC-associated upper GI lesions and COVID-19.
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