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Post-discharge opioid utilization patterns in orthopedic patients are underestimated: an explorative study
Sanne A M Hendrickx1, Ellie B M Landman1, Ydo V Kleinlugtenbelt1
1Department of Orthopaedic and Trauma Surgery, Deventer Ziekenhuis, SE Deventer, the Netherlands.
Aim:
This study explores morphine use among patients after discharge following total hip (THA) or knee arthroplasty (TKA).
Method:
Morphine use was monitored for 14 days post-discharge. Patients recorded their morphine intake and reported pain using a Visual Analog Scale (VAS). Incomplete reports were excluded from longitudinal analysis. Median tablet count and total morphine use in milligram equivalents (MME) were calculated. Patients were categorized as non-users (0 mmE), short-term users (<100 mmE), and consistent users (>100 mmE).
Results:
Of the 67 patients, six dropped out. Among the remaining, 22 (36.7%) took no morphine, while 38 (63.3%) took at least one dose, with a median VAS-score of 5. Short-term users (n = 19) averaged a total of 40 mmE, mainly in the first three days, while consistent users (n = 15) averaged in total 220 mmE during follow-up, tapering gradually. After 14 days, 3% continued usage. Four patients with incomplete data were excluded. However, for those was found that this was due to or related to the fact that they used a large amount of morphine.
Conclusion:
Most patients used minimal or no morphine, tapering off within two weeks.
Insights
Most patients undergoing hip or knee replacement surgery used minimal morphine post-discharge. Opioid use generally tapered within 14 days, with few patients requiring long-term pain management.
Area of Science:
- Orthopedic Surgery
- Pain Management
- Pharmacology
Background:
- Post-operative pain management is crucial after total hip (THA) and knee arthroplasty (TKA).
- Understanding patient opioid consumption patterns is essential for optimizing pain control and minimizing risks.
Purpose of the Study:
- To investigate morphine utilization patterns in patients following THA and TKA.
- To quantify morphine use and identify patient subgroups based on consumption levels.
Main Methods:
- Prospective monitoring of morphine intake for 14 days post-discharge.
- Patients recorded morphine use and pain scores (Visual Analog Scale).
- Morphine use was categorized into non-users, short-term users (<100 MME), and consistent users (>100 MME).
Main Results:
- 63.3% of patients used morphine post-discharge, with a median VAS score of 5.
- Short-term users (n=19) averaged 40 MME, primarily in the first three days.
- Consistent users (n=15) averaged 220 MME, with gradual tapering; only 3% continued use after 14 days.
Conclusions:
- The majority of patients require minimal morphine after THA/TKA.
- Opioid use typically decreases significantly within two weeks post-surgery.
- Further investigation may be warranted for patients with high morphine consumption.
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