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Updated: May 24, 2025

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Aging Impacts Basic Auditory and Timing Processes.

Antonio Criscuolo1, Michael Schwartze1, Leonardo Bonetti2,3,4

  • 1Department of Neuropsychology & Psychopharmacology, Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, the Netherlands.

The European Journal of Neuroscience
|March 3, 2025
PubMed
Summary
This summary is machine-generated.

Aging affects auditory processing, leading to difficulties in speech comprehension. Older adults show altered neural responses and reduced phase alignment when processing predictable sound sequences, impacting basic timing abilities.

Keywords:
EEGagingauditionoscillationstiming

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Area of Science:

  • Neuroscience
  • Auditory Neuroscience
  • Cognitive Aging

Background:

  • Age-related hearing and speech comprehension difficulties are common.
  • Electrophysiological data in older adults show altered neural responses and phase alignment variability along the auditory pathway.
  • It is unclear if aging-related speech processing challenges stem from fundamental auditory and timing deficits.

Purpose of the Study:

  • To investigate how aging individuals encode temporal regularities in isochronous auditory sequences.
  • To examine adaptive neural phase alignment mechanisms in anticipation of sound onsets in aging.
  • To determine if basic auditory and timing processes are impaired in older adults.

Main Methods:

  • Electroencephalography (EEG) was recorded in older and young individuals.
  • Participants listened to simple isochronous tone sequences at 1.5Hz.
  • Analysis focused on neural responses, 1/F slope, and phase-coherence in delta and theta frequency bands.

Main Results:

  • Older adults exhibited larger event-related neural responses and an increased 1/F slope.
  • Reduced phase-coherence at the stimulation frequency (1.5Hz) was observed in aging individuals.
  • A reduced slope of phase-coherence over time in delta and theta bands suggests altered neural phase alignment mechanisms.

Conclusions:

  • Aging is associated with altered top-down modulatory inhibition in processing predictable auditory sequences.
  • Mechanisms of continuous neural phase alignment to expected sound onsets are impaired in aging.
  • Deficits in basic auditory timing capacities in aging may impact higher-order cognitive functions, necessitating further research across the lifespan.