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Published on: December 10, 2020
Perfusion Index Predicts the Effectiveness of Supraclavicular Brachial Plexus Block in Children Under General
Tiantian Chu1, Siqi Zhou1, Ting Peng1
1Department of Anaesthesiology, Hubei Key Laboratory of Geriatric Anaesthesia and Perioperative Brain Health, and Wuhan Clinical Research Center for Geriatric Anaesthesia, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Insights
Perfusion index (PI) has limited ability to predict supraclavicular block (SCB) effectiveness in children under general anesthesia. However, PI may help guide pain management in the post-anesthesia care unit (PACU).
Area of Science:
- Anesthesiology
- Pediatric Surgery
- Regional Anesthesia
Background:
- Supraclavicular block (SCB) is used for pediatric upper extremity surgery.
- Assessing SCB effectiveness under general anesthesia (sevoflurane or propofol) is crucial.
- Perfusion index (PI) is a non-invasive measure from pulse oximetry.
Purpose of the Study:
- To evaluate the predictive value of perfusion index (PI) for SCB effectiveness in children.
- To compare PI's predictive ability under sevoflurane versus propofol anesthesia.
- To assess PI's utility in guiding postoperative analgesia.
Main Methods:
- Randomized controlled trial involving 103 pediatric patients undergoing upper extremity surgery.
- Patients received either sevoflurane or propofol general anesthesia with SCB.
- PI was measured using pulse oximetry at various time points.
Main Results:
- PI increased post-anesthesia but showed no significant difference between anesthetic groups.
- At 10 minutes post-SCB, PI was higher on the blocked side, but with low predictive sensitivity and specificity.
- In the PACU, PI demonstrated higher sensitivity and specificity for predicting SCB effectiveness.
Conclusions:
- PI has limited value in predicting immediate SCB effectiveness (10 min post-block) under general anesthesia.
- PI may be a useful indicator for determining the need for supplemental analgesia in the PACU.
- Further research could refine PI's role in guiding pain management post-SCB.
Abstract:
Objectives: This study aimed to assess the predictive value of perfusion index (PI) in determining the effectiveness of supraclavicular block (SCB) in children under sevoflurane or propofol general anesthesia. Methods: In this randomized controlled study, 104 children who underwent elective upper extremity surgery under sevoflurane or propofol anesthesia were scheduled to be enrolled. The primary outcome was the effects of PI in predicting the effectiveness of SCB under general anesthesia. The PI value was obtained through pulse oximetries. Secondary outcomes include hemodynamic data, supplementary opioid doses, agitation score, pain score, and postoperative complications. Results: A total of 103 pediatric patients were analyzed. PI increased rapidly after anesthesia induction, and there was no significant difference in PI in the blocked side between the propofol group (PRO group) and sevoflurane group (SEV group). At 10 min after the block, PI in the blocked side was higher than that in the unblocked side in both groups (p < 0.05). However, PI showed low sensitivity and specificity in predicting the effect of SCB at 10 min in both groups. At PACU, PI exhibited a high sensitivity (0.837 vs. 0.796) and specificity (0.721 vs. 0.898) for SCB at cutoff values of 5.91 and 6.67 in both PRO and SEV groups. The area under the receiver operating characteristic curve (AUROC) values were 0.834 (95% CI 0.750-0.918) and 0.895 (95% CI 0.832-0.959). Conclusion: PI demonstrates limited sensitivity and specificity in predicting the effect of SCB at 10 min after block under general anesthesia. However, PI may serve as a more appropriate indicator to guide the necessity for supplemental analgesia in PACU. Trial Registration: ClinicalTrials.gov identifier: NCT04216823.
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