Clostridium Cadaveris Bacteremia in an Immunocompromised Host

Clostridial bacteremia is an exceedingly rare clinical entity that can cause significant morbidity and mortality. Immunocompromised patients with insult to the gastrointestinal mucosa are especially prone to the development of clostridial sepsis based on limited existing literature. Here we report a case of a 65-year-old male nursing home resident with incompletely treated colorectal adenocarcinoma who was admitted for sepsis. He was found to have polymicrobial bacteremia with Escherichia coli and Clostridium cadaveris. He was successfully treated with intravenous piperacillin/tazobactam followed by an oral regimen of amoxicillin/clavulanic acid.