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Related Concept Videos

Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

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Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
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Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
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Intracellular bacteria and viruses often comprise a group of highly infectious pathogens that can cause several diseases. Bacterial pathogens include those belonging to the genus Rickettsia responsible for conditions such as rocky mountain spotted fever and the Mediterranean spotted fever; Chlamydia, a genus responsible for a sexually transmitted disease; Coxiella burnetii, an agent responsible for Q fever. Viral pathogens include vaccinia—a poxvirus, and herpes simplex virus—a...
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Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
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Pulmonary Tuberculosis I01:29

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Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
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Acute Pharyngitis01:30

Acute Pharyngitis

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Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
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Related Experiment Video

Updated: May 24, 2025

Author Spotlight: Controlled Human Exposure Model for Tick Research and Lyme Disease Studies
04:47

Author Spotlight: Controlled Human Exposure Model for Tick Research and Lyme Disease Studies

Published on: December 1, 2023

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Ticked-Off Rash.

Rakin Solaiman1,2,3, Jeff Kilcup1, Samuel Josephsen2

  • 1Department of Infectious Diseases Wake Forest University School of Medicine.

Journal of Brown Hospital Medicine
|March 3, 2025
PubMed
Summary
This summary is machine-generated.

A tick bite led to a Francisella tularensis infection, causing severe systemic symptoms and a rash in an elderly woman. Prompt diagnosis is crucial for effective treatment of this rare bacterial disease.

Keywords:
escharinfectious diseasetick borne illnesstularemiazoonotic infection

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Area of Science:

  • Infectious Diseases
  • Bacteriology
  • Public Health

Background:

  • Tularemia is a zoonotic disease caused by Francisella tularensis, often associated with wild animals and arthropod vectors.
  • Early symptoms can be non-specific, including fever, malaise, and weight loss, potentially mimicking other conditions like cellulitis.
  • Prompt and accurate diagnosis is essential for effective treatment and preventing severe complications.

Observation:

  • An 89-year-old female presented with high-grade fever, malaise, and unintentional weight loss.
  • A rash, initially presumed to be non-purulent cellulitis, was noted.
  • Despite multiple antibiotic courses, her symptoms worsened, necessitating hospitalization.

Findings:

  • Blood cultures were positive for Francisella tularensis.
  • A detailed history revealed a tick bite during a camping trip preceding the rash.
  • The clinical presentation and laboratory results confirmed a diagnosis of tularemia.

Implications:

  • This case highlights the importance of considering tularemia in elderly patients with unexplained systemic symptoms and rash, especially after potential vector exposure.
  • Tick-borne illnesses require a high index of suspicion, even with atypical presentations.
  • Early recognition and appropriate antibiotic therapy are critical for favorable outcomes in tularemia.