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The Combined Use of Transcranial Direct Current Stimulation and Robotic Therapy for the Upper Limb

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Breaking Barriers in Stroke Therapy: Recent Advances and Ongoing Challenges.

Akkila Goud Bakka¹, Shweta Shirish Patil¹, Bhavagna Rachakonda¹

¹Department of Pharmacology, RVM Institute of Medical Sciences and Research Center, Laxmakkapally, IND.

|March 3, 2025

Summary

Advancements in acute ischemic stroke care include improved diagnostics, mobile stroke units, and enhanced therapies like thrombolysis and mechanical thrombectomy. Continued innovation and equitable access are crucial for better patient outcomes.

Keywords:

biomarkers ischemic stroke mechanical thrombectomy stroke management thrombolytic therapy

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Area of Science:

Neurology
Cardiovascular Medicine
Public Health

Background:

Acute ischemic stroke is a major global health concern.
Significant progress has been made in stroke management, diagnostics, and therapeutics.
Timely intervention is critical, as highlighted by the 'time is brain' principle.

Purpose of the Study:

To review recent advancements in acute ischemic stroke management.
To highlight innovations in diagnostics, pre-hospital care, and therapeutic interventions.
To discuss challenges and future directions in stroke care, including emerging technologies.

Main Methods:

Review of diagnostic innovations (imaging, biomarkers).
Analysis of therapeutic breakthroughs (thrombolysis, mechanical thrombectomy).
Examination of post-stroke care models (rehabilitation, telemedicine) and emerging technologies (AI, machine learning).

Main Results:

Improved early detection and treatment precision through advanced diagnostics.
Expedited pre-hospital care via mobile stroke units.
Enhanced treatment efficacy and broader applicability of thrombolytic therapy and mechanical thrombectomy.
Personalized rehabilitation and telemedicine expanding post-stroke care access.
Emerging technologies like AI show promise for risk prediction and early intervention.

Conclusions:

Transformative progress has been achieved in acute stroke care.
Challenges remain, including access disparities and management of minor strokes.
Continued innovation, research, and equitable access are essential for improving patient outcomes.