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Updated: May 24, 2025

A Gut-on-a-Chip Model to Study the Gut Microbiome-Nervous System Axis
Published on: July 28, 2023
Gut-X axis
Xu Lin1, Zuxiang Yu2, Yang Liu3
1Department of Endocrinology and Metabolism Shunde Hospital of Southern Medical University (The First People's Hospital of Shunde) Foshan City 528308 China.
Abstract:
Recent advances in understanding the modulatory functions of gut and gut microbiota on human diseases facilitated our focused attention on the contribution of the gut to the pathophysiological alterations of many extraintestinal organs, including the liver, heart, brain, lungs, kidneys, bone, skin, reproductive, and endocrine systems. In this review, we applied the "gut-X axis" concept to describe the linkages between the gut and other organs and discussed the latest findings related to the "gut-X axis," including the underlying modulatory mechanisms and potential clinical intervention strategies.
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