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Yoga Intervention and Inflammatory Homoeostasis in Breast Cancer Patients
Kaini Cecilia Kaje1, Fatima Dsilva1, Praveen Kumar Shetty2
1Department of Medical Surgical Nursing, Nitte Usha Institute of Nursing Sciences, NITTE (Deemed to be University), Mangaluru, Karnataka, India.
Indian Journal of Palliative Care
|March 3, 2025
Summary
Yoga complementary therapy significantly improved breast cancer patient outcomes by reducing inflammatory markers like tumor necrosis factor-alpha and interleukins. This supports yoga
Area of Science:
- Oncology
- Integrative Medicine
- Immunology
Background:
- Yoga is increasingly used as supportive therapy in breast cancer treatment.
- Patients seek complementary approaches to enhance well-being during conventional therapy.
- Inflammatory markers play a role in breast cancer progression and treatment side effects.
Purpose of the Study:
- To investigate the impact of yoga intervention on inflammatory homeostasis in newly diagnosed breast cancer patients.
- To assess changes in key inflammatory markers during neoadjuvant chemotherapy.
Main Methods:
- Prospective non-randomized control study with 44 newly diagnosed breast cancer patients (Stages II-IV).
- Yoga intervention group compared to a control group.
- Biomarker assessments conducted pre-chemotherapy, during chemotherapy, pre-surgery, and post-surgery.
Main Results:
- Significant within-subject reduction in serum tumor necrosis factor-alpha, interleukin-1 beta, and interleukin-6 in the yoga group.
- No significant changes observed in the control group.
- Trend towards downregulation of proinflammatory markers over time in the yoga intervention group.
Conclusions:
- Yoga as a complementary therapy can modulate proinflammatory markers in breast cancer patients.
- This modulation may contribute to improved health outcomes during conventional treatment.
- Yoga shows potential in supporting breast cancer patients by managing inflammation.
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