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Updated: May 24, 2025

Synthesis of Hypervalent Iodonium Alkynyl Triflates for the Application of Generating Cyanocarbenes
Published on: September 8, 2013
Direct Cyclization of 1,3-Diketones with Malonate-Based Iodonium Ylides to Generate Dihydrofurans
Zhiguo Zhao1, Ziqiang Zhao1, Yuanling Pang1
1School of Chemistry and Chemical Engineering, Key Laboratory of the Colloid and Interface Chemistry of the Ministry of Education, Shandong University, Jinan, 250100, China.
Abstract:
While iodonium ylides are important reactants in a wide range of reactions, the exploration of electron-transfer property of iodonium ylides remains an underdeveloped topic. Herein, we describe a direct cyclization of 1,3-diketones with malonate-based iodonium ylides to give a diverse array of dihydrofurans in moderate yields. The control experiments suggest that the electron transfer between enol and iodonium ylide gives reactive species, thus enabling a cyclization cascade process to take place to give dihydrofurans.
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