Multiclass plaque segmentation of coronary artery disease patients using an enhanced model

Ting Chen1, Xing Wang2, Xinliu He1

  • 1School of Medical Imaging, Department of Medical Technology, Tianjin Medical University, Tianjin, China.

Medical Physics
|March 3, 2025
PubMed

Insights

Automated analysis of intravascular optical coherence tomography (IVOCT) data using an enhanced DeepLabV3+ model improves plaque segmentation for coronary artery disease (CAD) patients, aiding personalized treatment.

Area of Science:

  • Cardiovascular Imaging
  • Artificial Intelligence in Medicine
  • Medical Image Analysis

Background:

  • Coronary artery plaque analysis is crucial for personalized treatment in coronary artery disease (CAD).
  • Intravascular optical coherence tomography (IVOCT) offers detailed plaque characterization.

Purpose of the Study:

  • To develop automated methods for rapid and accurate analysis of IVOCT data.
  • To enable cardiologists in providing tailored treatments for CAD patients.

Main Methods:

  • Integration of two coordinate image types with an enhanced DeepLabV3+ model.
  • Direct three-class segmentation for fibrous, lipid, and calcified plaques.
  • Data split into 7:2:1 for training, validation, and testing.

Main Results:

  • The enhanced DeepLabV3+ model achieved plaque-level F1 scores of 0.855 (fiber), 0.850 (lipid), and 0.551 (calcified).

Conclusions:

  • The study demonstrates potential for improved accuracy and efficiency in CAD plaque segmentation.
  • Enhanced automated analysis can lead to more personalized and effective patient treatments.
Abstract