Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Adsorption of Zwitterionic and Capped Amino Acids to Graphene: A Molecular Dynamics Study.

ACS omega·2026

Same author

Leveraging the dominant-negative effect of the kuru-protective G127V prion protein variant as a novel therapeutic strategy.

Neurobiology of disease·2026

Same author

Emerging risks at the vampire bat-prion interface: implications for wildlife, livestock, and public health.

Journal of mammalogy·2026

Same author

Leveraging the dominant-negative effect of the kuru-protective G127V prion protein variant as a novel therapeutic strategy.

bioRxiv : the preprint server for biology·2026

Same author

Consequences of prion strain mixtures: Indifference, competition, or collusion.

PLoS pathogens·2026

Same author

Prion seeding activity in DNA extractions: implications for laboratory biosafety.

Prion·2026

Same journal

A Video Protocol of a Randomized Controlled Clinical Trial - Electrochemotherapy of Cutaneous Metastases with Reduced Dose Bleomycin (BLESS Trial).

Journal of visualized experiments : JoVE·2026

Same journal

A Standardized Ex Vivo Porcine Oromucosal Model for Evaluating Peptide Fluxes.

Journal of visualized experiments : JoVE·2026

Same journal

Lightweight English Text Classification with Deep Learning Based on Complex System Theory.

Journal of visualized experiments : JoVE·2026

Same journal

Integrating Artificial Intelligence-Assisted Translation Support into English Courses: Effects on Translation Accuracy, Perceived Stress, and Anxiety.

Journal of visualized experiments : JoVE·2026

Same journal

A Toxin-Based Counter-Selection System for Markerless Gene Deletion and High-Density Tn5 Transposon Mutagenesis in Pectobacterium brasiliense.

Journal of visualized experiments : JoVE·2026

Same journal

Seamless Multimodal Human-Robot Communication: Integration Techniques in Human-Computer Interaction.

Journal of visualized experiments : JoVE·2026

See all related articles

Search research articles

Related Experiment Video

Updated: May 24, 2025

Prion Safety Laboratory Swipe Test

Prion Safety Laboratory Swipe Test

Published on: February 14, 2025

Prion Safety Laboratory Swipe Test.

Sara M Simmons¹, Qi Yuan¹, Jason C Bartz²

¹Department of Medical Microbiology and Immunology, School of Medicine, Creighton University.

Journal of Visualized Experiments : Jove

|March 3, 2025

Summary

This summary is machine-generated.

A new laboratory swipe test protocol helps detect prion contamination on surfaces, addressing the challenge of prion persistence and resistance to inactivation. This method aids in assessing decontamination effectiveness and monitoring laboratory safety.

More Related Videos

Procedures for Identifying Infectious Prions After Passage Through the Digestive System of an Avian Species

Procedures for Identifying Infectious Prions After Passage Through the Digestive System of an Avian Species

Published on: November 6, 2013

Assessing Transmissible Spongiform Encephalopathy Species Barriers with an In Vitro Prion Protein Conversion Assay

Assessing Transmissible Spongiform Encephalopathy Species Barriers with an In Vitro Prion Protein Conversion Assay

Published on: March 10, 2015

Related Experiment Videos

Last Updated: May 24, 2025

Prion Safety Laboratory Swipe Test

Prion Safety Laboratory Swipe Test

Published on: February 14, 2025

Procedures for Identifying Infectious Prions After Passage Through the Digestive System of an Avian Species

Procedures for Identifying Infectious Prions After Passage Through the Digestive System of an Avian Species

Published on: November 6, 2013

Assessing Transmissible Spongiform Encephalopathy Species Barriers with an In Vitro Prion Protein Conversion Assay

Assessing Transmissible Spongiform Encephalopathy Species Barriers with an In Vitro Prion Protein Conversion Assay

Published on: March 10, 2015

Area of Science:

Neuroscience
Infectious Diseases
Biochemistry

Background:

Iatrogenic prion diseases can spread via contaminated surgical tools and laboratory materials.
Prions, misfolded proteins, cause fatal neurodegenerative diseases.
Prions are highly resistant to inactivation and persist on surfaces, posing risks in laboratory settings.

Purpose of the Study:

To develop and describe a protocol for a prion safety laboratory swipe test.
To assess the effectiveness of decontamination procedures for prion-contaminated surfaces.
To monitor laboratory environments for potential prion contamination.

Main Methods:

The protocol involves identifying high-traffic laboratory areas for testing.
It includes recommended swabbing controls to ensure result validity.
Steps for responding to positive results and identifying artifactual results are detailed.

Main Results:

The swipe test protocol provides a method for detecting prion contamination on surfaces.
It allows for the documentation of decontamination status in prion safety laboratories.
Representative results and potential artifactual findings are discussed.

Conclusions:

The prion safety laboratory swipe test can be integrated into broader prion safety programs.
It assists in assessing surface decontamination and monitoring common laboratory spaces.
The test supports the documentation of prion decontamination status to enhance laboratory safety.