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Scaled modeling is a fundamental technique in engineering, enabling the study of large and complex systems by creating smaller, manageable replicas that recreate critical characteristics of the original. In hydrology and civil infrastructure, for example, scaled models of dams help analyze water flow, turbulence, and pressure. This method allows for accurate predictions of real-world behavior within a controlled environment, significantly reducing the cost and time involved in full-scale...
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Clearance measures drug elimination from the central compartment, including plasma and highly perfused organs like kidneys and liver. Its calculation varies depending on pharmacokinetic models and administration routes. The one-compartment model, for instance, portrays the pharmacokinetics of polar drugs such as aminoglycoside antibiotics administered intravenously and readily excreted in urine. In this case, clearance is influenced by the terminal rate constant (λz) and the total volume...
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Multicompartment models are mathematical constructs that depict how drugs are distributed and eliminated within the body. They segment the body into several compartments, symbolizing various physiological or anatomical areas connected through drug transfer processes such as absorption, metabolism, distribution, and elimination.
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The three-compartment open model is a pharmacokinetic model used to describe the distribution and elimination of drugs following extravascular administration. It comprises a central compartment representing the plasma and two peripheral compartments. The highly perfused peripheral compartment represents organs and tissues with a rich blood supply, such as the liver, kidneys, and lungs. The scarcely perfused peripheral compartment represents tissues with lower blood supply, such as adipose...
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Related Experiment Video

Updated: May 24, 2025

Quantification of Strain in a Porcine Model of Skin Expansion Using Multi-View Stereo and Isogeometric Kinematics
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Single-View Clothed Human Reconstruction With Multi-View Consistency Representation.

Zhuo Su, Yudi Tan, Zedan Zheng

    IEEE Transactions on Visualization and Computer Graphics
    |March 3, 2025
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    Summary
    This summary is machine-generated.

    This study introduces a novel method for single-view clothed human reconstruction, improving depth accuracy and handling invisible areas. The approach enhances feature representation for more precise 3D human models.

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    Area of Science:

    • Computer Vision
    • 3D Reconstruction
    • Machine Learning

    Background:

    • Single-view clothed human reconstruction faces challenges with depth ambiguity and missing invisible information.
    • Existing PIFu-like frameworks rely on pixel-aligned features, leading to representation inaccuracies.

    Purpose of the Study:

    • To address depth ambiguity and the lack of invisible information in single-view clothed human reconstruction.
    • To enhance the accuracy and detail of 3D human models generated from single images.

    Main Methods:

    • Proposed a depth-guided pixel-aligned feature to filter features based on depth discrepancies.
    • Introduced multi-view consistency prior using contrastive learning and masked autoencoder for SMPL vertex features.
    • Constrained representation learning to focus on visible parts and infer invisible information.

    Main Results:

    • The proposed method significantly improves feature representation for surface details.
    • Achieved more reasonable and accurate representation learning in single-view reconstruction.
    • Demonstrated superior performance compared to previous implicit representation-based methods on public and commercial datasets.

    Conclusions:

    • The novel approach effectively tackles key limitations in single-view clothed human reconstruction.
    • The method provides a more robust and accurate way to generate detailed 3D human models.
    • This work advances the state-of-the-art in implicit 3D human shape and appearance reconstruction.