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Operability of intracranial meningiomas. Personal series of 353 cases
Abstract:
The senior author's experience has been reviewed in 353 operated meningiomas; so called "malignant meningiomas" have been discarded. The whole series has been split into two groups: the first (A) includes 273 cases operated before the CT era, the second (B) consists of 80 cases the operability of which was based mainly on the CT. In addition, during the time elapsed to constitute the second series surgery has been refused to 15 patients which were considered for CT and clinical reasons as surgically incurable when one wants to reduce the risk of mortality and morbidity. Therefore, we have reviewed in series B indisputable, questionable and incurable cases with respect to operability in the present condition of our technical possibilities including arterial hypotension, the operative microscope and the CUSA. Considering localization, we have made technical observations with respect to the principles on which operations have been based since 1958 when general anaesthesia became available in La Pitié. Among the patients of the whole series, 14 were admitted for a recurrence. The time interval between surgery and readmission has been given as well as the primary location of the meningiomas. The mortality rate has been 26 out of 353 (7%), and the main causes have been reviewed especially in series B. With regard to series B, we have been able to get in touch with 53 patients out of 80; 90% of them returned to work or family without sequelae. Intracranial meningiomas remain the most curable tumours, nevertheless some of them must be considered incurable like in meningiomatosis or when the dural attachment is extensive. For those cases surgery is not the final answer and we must accept the fact that in the future other kinds of treatment will develop.
Insights
This study reviews 353 operated meningiomas, comparing outcomes before and after the CT scan era. Advanced surgical techniques improve outcomes, though some meningiomas remain incurable.
Area of Science:
- Neurosurgery
- Oncology
- Radiology
Background:
- Meningiomas are primary tumors of the meninges.
- Surgical management of meningiomas has evolved significantly.
- Computed Tomography (CT) has revolutionized surgical planning.
Purpose of the Study:
- To review the senior author's experience with 353 operated meningiomas.
- To compare surgical outcomes before and after the widespread adoption of CT scans.
- To evaluate current surgical techniques and their impact on meningioma treatment.
Main Methods:
- Retrospective review of 353 operated meningiomas.
- Division of cases into two groups: pre-CT era (273 cases) and CT era (80 cases).
- Analysis of surgical techniques, including arterial hypotension, operative microscope, and CUSA, and their impact on outcomes.
Main Results:
- Overall mortality rate of 7% (26 out of 353).
- In the CT era group (Series B), 90% of contacted patients (53/80) returned to work or family without sequelae.
- Recurrence was noted in 14 patients, with analysis of time interval and primary location.
Conclusions:
- Intracranial meningiomas are generally curable tumors.
- Certain cases, such as extensive dural attachments or meningiomatosis, remain challenging and potentially incurable with surgery alone.
- Future treatments may offer alternative solutions for currently incurable meningiomas.