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A Gran plot is used to predict the equivalence volume or endpoint of a potentiometric or acid-base titration without reaching the endpoint. Typically, titration data is collected as a function of the titrant's volume up to a point less than the equivalence volume and then transformed into a linear format. The straight line is extended to the x-axis, indicating the necessary titrant volume to achieve the equivalence point.
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Updated: May 24, 2025

Temporal Ordering of Dynamic Expression Data from Detailed Spatial Expression Maps
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Boosting Temporal Graph Learning From Perspectives of Global and Local Structures.

Fengyi Wang, Guanghui Zhu, Hongqing Ding

    IEEE Transactions on Neural Networks and Learning Systems
    |March 3, 2025
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    Summary
    This summary is machine-generated.

    The Global and Local Embedding Network (GLEN) enhances temporal graph representation learning by combining global and local node perspectives. This approach improves performance on dynamic node classification and link prediction tasks.

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    Area of Science:

    • Artificial Intelligence
    • Machine Learning
    • Graph Neural Networks

    Background:

    • Temporal graph learning is crucial for applications requiring analysis of dynamic network structures.
    • Existing methods often focus on either global or local graph perspectives, limiting their ability to capture complex temporal dynamics.
    • A gap exists in effectively integrating complementary global and local information for robust temporal graph representation learning.

    Purpose of the Study:

    • To propose the Global and Local Embedding Network (GLEN) for effective and efficient temporal graph representation learning.
    • To address the limitations of existing methods in capturing complex dynamic patterns by considering both global and local node information.
    • To improve the performance of temporal graph learning tasks such as link prediction and dynamic node classification.

    Main Methods:

    • GLEN dynamically generates node embeddings by integrating global and local perspectives using specialized modules.
    • A cross-perspective fusion module combines global and local embeddings to capture high-order semantic relationships.
    • The network is designed for efficient computation and effective representation learning on temporal graphs.

    Main Results:

    • GLEN significantly outperforms baseline methods on multiple real-world datasets for both link prediction and dynamic node classification tasks.
    • Experimental results validate the effectiveness of integrating global and local perspectives for temporal graph learning.
    • The proposed method demonstrates superior performance under stringent evaluation protocols.

    Conclusions:

    • GLEN provides a novel and effective approach to temporal graph representation learning by synergizing global and local node embeddings.
    • The method achieves a superior balance between inference precision and training efficiency.
    • GLEN offers a promising solution for complex dynamic network analysis and various downstream applications.