Cardiovascular disease in people living with HIV: Risk assessment and management

Elizabeth Ghandakly1, Rohit Moudgil2, Katherine Holman3

  • 1Department of Internal Medicine, Cleveland Clinic, Cleveland, OH ghandae@ccf.org.

Insights

People living with human immunodeficiency virus (HIV) face earlier and increased cardiovascular disease (CVD) risk. Careful assessment and management of CVD risk factors are crucial for this population.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Public Health

Background:

  • Human immunodeficiency virus (HIV) infection affects nearly 40 million people globally.
  • Advances in treatment have transformed HIV into a manageable chronic condition for many.
  • Individuals with HIV experience a substantially elevated risk and earlier onset of cardiovascular disease (CVD).

Purpose of the Study:

  • To highlight the increased cardiovascular risk in people living with HIV.
  • To emphasize the need for proactive cardiovascular risk assessment and management in this demographic.

Main Methods:

  • Review of current understanding of HIV and cardiovascular health.
  • Analysis of factors contributing to CVD risk in the HIV population.

Main Results:

  • People with HIV develop coronary artery disease significantly earlier than the general population.
  • Chronic inflammation, biochemical factors, social determinants, and nonbiologic factors contribute to heightened CVD risk.

Conclusions:

  • Cardiovascular risk management is essential for individuals living with HIV.
  • Early and vigilant attention to CVD risk assessment and management is critical for improving long-term health outcomes in people with HIV.

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