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A Dual-Channel Fluorescent Probe for Detection of Biothiols in Green and Further Differentiation of Cys/Hcy in
Yuyuan Sun1, Hui Wang2, Xulong He1
1School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou, China.
Abstract:
Biothiols like cysteine and homocysteine have important physiological activities in organisms. Therefore, the effective monitoring of such substances holds special significance. In this work, a dual-channel fluorescent probe DEHQ-NBD was developed for the detection of biothiols in green and further differentiation of Cys/Hcy in NIR regions. Meanwhile, the probe exhibits good photostability, rapid response, and low cytotoxicity, which has been successfully applied in cell imaging.

