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Bone density comparison between the normal pedicle trajectory, cortical bone trajectory, and modified cortical bone
Bikash Parajuli1, Dipak Shrestha1, Kuniyoshi Abumi2
1Department of Orthopaedics and Traumatology, Dhulikhel Hospital/Kathmandu University Hospital, Dhulikhel, Nepal.
Asian Spine Journal
|March 4, 2025
Summary
Modified cortical bone trajectory (MCBT) offers superior bone density for lumbar spine fixation compared to original pedicle trajectory (OPT). MCBT provides posterior cortical bone density comparable to cortical bone trajectory (CBT), suggesting it as a viable alternative.
Area of Science:
- Spine surgery
- Orthopedic biomechanics
- Radiology
Background:
- Cortical bone trajectory (CBT) offers improved screw fixation due to enhanced bone contact.
- However, CBT may limit screw size and fixation depth within the vertebral body.
- Original pedicle trajectory (OPT) is a traditional method with known limitations.
Purpose of the Study:
- To compare bone density using computed tomography Hounsfield units (CTHU) among original pedicle trajectory (OPT), cortical bone trajectory (CBT), and modified cortical bone trajectory (MCBT).
Main Methods:
- A cross-sectional study analyzed computed tomography scans of 1,000 lumbar vertebrae (L1-L5) from 200 patients.
- Bone density (CTHU) was measured at four points (posterior cortex, mid-pedicle, midbody, anterior cortex) for OPT, CBT, and MCBT planes.
- Statistical analysis compared CTHU values across trajectories and evaluated age-related bone density decline.
Main Results:
- Mean CTHU values were significantly different: OPT (354.2±70 HU), CBT (529.9±75 HU), and MCBT (457.3±90 HU) (p <0.01).
- MCBT's posterior cortex CTHU was 65.6% higher than OPT and 14.9% lower than CBT.
- Bone density decline with age was less pronounced in MCBT and CBT compared to OPT.
Conclusions:
- Modified cortical bone trajectory (MCBT) demonstrates significantly higher bone density than original pedicle trajectory (OPT).
- MCBT achieves posterior cortical bone density comparable to CBT.
- MCBT presents a promising alternative trajectory for lumbar spine fixation.

