Related Experiment Video
Updated: May 18, 2026

Immuno-fluorescence Assay of Leptospiral Surface-exposed Proteins
Published on: July 1, 2011
Acute Leptospirosis Outbreak in Cattle: A Case Report.
Gustavo Paixão1,2,3,4, Sofia Botelho-Fontela2, Filipe Gandra4
1CISAS - Center for Research and Development in Agrifood Systems and Sustainability, Instituto Politécnico de Viana do Castelo, Viana do Castelo, Portugal.
This study details an acute bovine leptospirosis outbreak linked to climate conditions. Pomona and Mozdok serovars were prevalent, highlighting the need for vaccination and regional control strategies.
Area of Science:
- Veterinary Medicine
- Zoonotic Diseases
- Epidemiology
Background:
- Leptospirosis, caused by Leptospira species, is a global zoonotic disease with varied clinical presentations in cattle.
- Infections range from subclinical chronic forms in adults to severe acute syndromes in calves.
Observation:
- An outbreak of acute bovine leptospirosis occurred following favorable climatic conditions across seven farms.
- Clinical signs included hyperacute disease and death in calves, and apathy, anorexia, jaundice, and hemoglobinuria in older cattle.
Findings:
- Necropsies confirmed jaundice and hemoglobinuria, supporting a leptospirosis diagnosis.
- Hematology and serology confirmed the outbreak, with Pomona and Mozdok serovars being most prevalent (62.5%).
- Highest mean agglutination titers were observed for Pomona (1:1160) and Mozdok (1:700).
Implications:
- Oxytetracycline was used for treatment, with chemical metaphylaxis and prophylactic measures implemented.
- Climate change is predicted to increase leptospirosis outbreaks, necessitating comprehensive serological surveys for control.
- Vaccination is emphasized as a practical and effective prophylactic measure for regional control strategies.
More Related Videos
15:57Application of Long-term cultured Interferon-γ Enzyme-linked Immunospot Assay for Assessing Effector and Memory T Cell Responses in Cattle
Published on: July 11, 2015
06:05Author Spotlight: Leptospira DNA Detection in Water for Environmental Analysis and Disease Surveillance
Published on: June 14, 2024
Related Concept Videos
Bacterial Phylum Spirochaetes
Investigation of Disease Outbreaks
Clinical Significance of Antibiotic Resistance