Related Experiment Video
Updated: May 24, 2025

Synthesis and Bioconjugation of Thiol-Reactive Reagents for the Creation of Site-Selectively Modified Immunoconjugates
Published on: March 6, 2019
Three-step process for the synthesis of 10,11-dihydro-5H-dibenzo[b,f]azepin-10-ol derivatives
Farid M Sroor1, Thierry Terme2, Patrice Vanelle2
1Organometallic and Organometalloid Chemistry Department, National Research Centre 12622 Cairo Egypt faridsroor@gmx.de.
Abstract:
We reported the synthesis of 10,11-dihydro-5H-dibenzo[b,f]azepin-10-ol derivatives, a class of compounds that has been limitedly investigated in the literature. Our approach streamlines the synthetic process, allowing straightforward access to various substituted 10,11-dihydro-5H-dibenzo[b,f]azepin-10-ol derivatives. This advancement not only enhances the accessibility of these derivatives for further research but also contributes to the development of potential therapeutic agents targeting various medical conditions.
More Related Videos
08:51Scale-up Chemical Synthesis of Thermally-activated Delayed Fluorescence Emitters Based on the Dibenzothiophene-S,S-Dioxide Core
Published on: October 24, 2017
06:34Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides CHIPS
Published on: June 20, 2014
Related Concept Videos
Oxidation of Alkenes: Syn Dihydroxylation with Osmium Tetraoxide
Diels–Alder Reaction Forming Cyclic Products: Stereochemistry
Benzene to Phenol via Cumene: Hock Process
[4+2] Cycloaddition of Conjugated Dienes: Diels–Alder Reaction
Preparation of Diols and Pinacol Rearrangement
The reaction begins with transferring a proton from the acid catalyst to one of the hydroxyl groups, producing an oxonium ion.
Hydrolysis of Chlorobenzene to Phenol: Dow Process