Trend of HIV/AIDS disease burden in China from 1990 to 2021: An age-period-cohort model analysis
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View abstract on PubMed
Summary
This summary is machine-generated.The burden of HIV/AIDS in China increased significantly from 1990 to 2021. Future prevention strategies must target adolescents and the elderly to curb rising incidence and mortality rates.
Area Of Science
- Epidemiology
- Public Health
- Disease Burden Analysis
Background
- Understanding the evolving burden of HIV/AIDS in China is crucial for developing effective public health interventions.
- Decades of data are essential for informing targeted control strategies against HIV/AIDS.
Purpose Of The Study
- To systematically analyze the trends and burden of HIV/AIDS in China from 1990 to 2021.
- To evaluate the impact of age, period, and cohort on HIV/AIDS incidence, mortality, and disability-adjusted life-years (DALYs).
Main Methods
- Data systematically retrieved from the Global Burden of Disease (GBD) study 2021 for China.
- Analysis of HIV/AIDS burden using incidence, mortality, and DALYs.
- Application of Joinpoint regression and age-period-cohort models to assess trends and influencing factors.
Main Results
- HIV/AIDS incidence, mortality, and DALYs increased in China between 1990 and 2021 for both sexes.
- Age-standardized rates showed average annual increases, with peak risks observed in younger age groups (20-24) for incidence.
- Mortality and DALY risks consistently rose, particularly for older age groups and the 1945-1949 birth cohort.
Conclusions
- The overall HIV/AIDS burden in China has demonstrably increased over the study period.
- Future HIV/AIDS control strategies should prioritize education and prevention efforts targeting adolescents and the elderly.
- Addressing age-specific and cohort-specific risks is vital for comprehensive HIV/AIDS management in China.
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