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Standing Waves in a Cavity

Standing Waves in a Cavity

A household microwave and lasers are examples of standing electromagnetic waves in a cavity. When two conducting metal plates are placed parallel at the nodal planes, it creates a cavity where standing waves are formed. The cavity between the two planes is analogous to a stretched string held at the points x = 0 and x = L. Here, the distance 'L' between the two planes must be an integer multiple of half of the wavelength. The wavelengths that satisfy this condition are given by:

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Development of Whispering Gallery Mode Polymeric Micro-optical Electric Field Sensors

Development of Whispering Gallery Mode Polymeric Micro-optical Electric Field Sensors

Published on: January 29, 2013

DNA Sensing with Whispering Gallery Mode Microlasers.

Soraya Caixeiro^1,2, Robert Dörrenhaus³, Anna Popczyk¹

¹Department of Chemistry and Biochemistry, Humboldt Centre for Nano- and Biophotonics, Institute for Light and Matter, Greinstrasse 4-6, 50939 Cologne, Germany.

|March 4, 2025

Summary

This study introduces a novel DNA-based sensor using whispering gallery mode (WGM) microlasers for real-time nucleic acid detection. The platform enhances sensitivity with gold nanoparticles and offers potential for diagnostics and drug delivery.

Keywords:

DNA hybridization DNA sensing hairpin substitution microlasers nucleic acid sensing oligonucleotides whispering gallery modes

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Last Updated: Jun 21, 2026

Development of Whispering Gallery Mode Polymeric Micro-optical Electric Field Sensors

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Published on: January 29, 2013

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Implementation of a Reference Interferometer for Nanodetection

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Published on: April 26, 2014

Area of Science:

Biotechnology
Nanotechnology
Biosensing

Background:

Nucleic acid sensing is vital for diagnostics and molecular research.
Precise identification of DNA and RNA interactions is key.

Purpose of the Study:

To develop an innovative sensing platform for real-time nucleic acid detection.
To enhance sensitivity and explore applications in diagnostics and drug delivery.

Main Methods:

Utilized DNA-functionalized whispering gallery mode (WGM) microlasers.
Correlated spectral shifts to refractive index changes for detection.
Incorporated gold nanoparticles and hairpin structures to enhance sensitivity and functionality.

Main Results:

Demonstrated real-time detection of DNA hybridization and structural changes.
Achieved enhanced sensitivity using gold nanoparticles and specific labeling strategies.
Showcased ionic strength influence on DNA compactness and a hairpin system for controlled release.

Conclusions:

The WGM-based platform provides a versatile tool for sequence-specific nucleic acid sensing.
The system shows promise for multiplexed detection and in vivo applications.
Potential applications include advanced diagnostics, therapeutic monitoring, and cellular research.