Hybrid ladybug Hawk optimization-enabled deep learning for multimodal Parkinson's disease classification using voice...

PD is a progressive neurodegenerative disorder that leads to gradual motor impairments. Early detection is critical for slowing the disease's progression and providing patients access to timely therapies. However, accurately detecting PD in its early stages remains challenging. This study aims to develop an optimized deep learning model for PD classification using voice signals and hand-drawn spiral images, leveraging a ZFNet-LHO-DRN. The proposed model first preprocesses the input voice signal using a Gaussian filter to remove noise. Features are then extracted from the preprocessed signal and passed to ZFNet to generate output-1. For the hand-drawn spiral image, preprocessing is performed with a bilateral filter, followed by image augmentation. Here also, the features are extracted and forwarded to DRN to form output-2. Both classifiers are trained using the LHO algorithm. Finally, from the output-1 and output-2, the best one is selected based on the majority voting. The ZFNet-LHO-DRN model demonstrated excellent performance by achieving a premium accuracy of 89.8%, a NPV of 89.7%, a PPV of 89.7%, a TNR of 89.3%, and a TPR of 90.1%. The model's high accuracy and performance indicate its potential as a valuable tool for assisting in the early diagnosis of PD.