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A Neuronal Apoptosis Model induced by Spinal Cord Compression in Rat
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Understanding degenerative cervical myelopathy in musculoskeletal practice
Matteo Cervellini1, Daniel Feller2,3,4, Filippo Maselli1,5
1Department of Human Neurosciences, Sapienza University of Rome, Rome, Italy.
The Journal of Manual & Manipulative Therapy
|March 4, 2025
Summary
Degenerative cervical myelopathy (DCM) presents challenges in early diagnosis due to overlapping symptoms and lack of screening tools. This review enhances physiotherapists
Area of Science:
- Neurology
- Spinal Cord Medicine
Background:
- Degenerative cervical myelopathy (DCM) involves spinal cord compression, often mimicking aging or carpal tunnel syndrome.
- Lack of validated screening tools complicates DCM diagnosis, risking delays and irreversible neurological damage.
- Limited awareness among public and healthcare professionals contributes to diagnostic challenges.
Purpose of the Study:
- To summarize and enhance physiotherapists' knowledge of DCM differential diagnosis and management.
- To provide essential information for understanding DCM and improving clinical reasoning.
- To guide clinicians on interdisciplinary collaboration and referral.
Main Methods:
- A comprehensive, non-systematic literature review was performed.
- The review covered DCM epidemiology, pathophysiology, clinical presentation, diagnostics, and management.
Main Results:
- The review provides essential knowledge to aid clinicians in understanding DCM.
- Enhanced clinical reasoning, examination interpretation, and performance are facilitated.
- Guidance on interdisciplinary collaboration and optimal referral is included.
Conclusions:
- This article aims to improve physiotherapists' understanding of DCM diagnosis and management.
- Enhanced knowledge can lead to earlier detection and better patient outcomes.
- Focus on differential diagnosis and appropriate referral is crucial for DCM patients.
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