Related Experiment Video
Updated: Jul 28, 2026
Cell-based Assay Protocol for the Prognostic Prediction of Idiopathic Scoliosis Using Cellular Dielectric Spectroscopy
Published on: October 16, 2013
Lactate concentration increase in female college students with idiopathic scoliosis: A cross-sectional study
Nawanto Agung Prastowo1, Maria Karen Tjhin1, Mariani Santosa1
1Department of Physiology, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia.
Purpose:
Scoliosis may create muscle imbalance and disturb muscle metabolism. However, no studies have examined muscle cell metabolism in scoliosis. This study evaluates lactate concentration in female college students with scoliosis.
Methods:
One hundred fifty female college students followed this cross-sectional analytic study. Inclusion and exclusion criteria were applied. Scoliosis was measured using a scoliometer. A scoliometer reading of 5° was considered scoliosis. Lactate concentration was measured using a lactate analyzer, and a lactate value above 2 mg dL-1 was denoted as 'elevated.' Anova and post hoc tests were used to analyze differences in the variables between scoliosis and normal subgroups. The results were significant if P < 0.05.
Results:
One hundred participants (66.7%) had a spinal curve angle of more than 5°. Only weight in thoracic scoliosis was lower than normal (P = 0.022). Lactate was significantly higher than normal in all scoliosis subtypes (P < 0.001). Lactate in both types was considerably higher than thoracic and lumbar scoliosis (P = 0.04 and 0.03, respectively).
Conclusion:
Lactate concentration increased in female students with scoliosis.
