Related Experiment Video
Updated: May 24, 2025
06:27
Establishment of Rat Models Mimicking Gender-affirming Hormone Therapies
Published on: January 10, 2025
663
Comments on Injectable Estradiol Use in Transgender and Gender-Diverse Individuals in the U.S
Christina Milano1, Joanna Harper2
1Department of Family Medicine, Oregon Health & Sciences University.
The Journal of Clinical Endocrinology and Metabolism
|March 4, 2025
Abstract
No abstract available in PubMed .
Keywords:
Estradiol injectionsestradiol cypionateestradiol valerategender-affirming hormone therapytransgenderMore Related Videos
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Drug delivery methods like oral inhalation, nasal sprays, transdermal patches, eye drops, intravitreal injection, and rectal administration provide localized effects with reduced toxicity.
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Transdermal patches transport drugs...
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Transdermal patches transport drugs...
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01:16Insulin: Dosing Regimen and Adverse Effects
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Insulin-replacement therapy usually includes both long-acting insulin (basal) and short-acting insulin (to cater to postprandial needs). In a diverse group of type 1 diabetes patients, the average daily insulin dose is typically 0.5-0.7 units/kg body weight. However, obese patients and pubertal adolescents may need more due to insulin resistance.
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
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01:22Birth Control Methods
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Vasectomy is a surgical form of male sterilization that involves severing and sealing the vasa deferentia, preventing sperm from mixing with semen during ejaculation. Because a vasectomy does not impact the testes' ability to produce testosterone, hormone levels, libido, and sexual function generally remain unchanged. While vasectomy is highly effective in preventing pregnancy, with a success rate near 99.85%, rare cases of recanalization (spontaneous reconnection) can occur. Although...
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01:18Drug Delivery: Enteral Route
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The enteral drug administration involves three primary routes: oral, sublingual, and buccal. Oral ingestion is the most prevalent, safe, economical, and convenient method for drug administration. However, it has certain drawbacks, including limited absorption due to the drug's low water solubility or poor membrane permeability, possible emesis from GI mucosa irritation, destruction of drugs by digestive enzymes or low gastric pH, and irregular absorption along with food or other drugs.
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01:29Drug Delivery: Parenteral Route
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The parenteral route is a critical method of drug administration. It delivers compounds directly into the systemic circulation and bypasses the gastrointestinal tract. This approach is particularly advantageous for drugs that exhibit poor absorption or instability when administered orally.
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01:30Adrenergic Agonists: Therapeutic Uses
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