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Updated: May 24, 2025

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Invasive Group B Streptococcal Disease Among Nonpregnant Adults: Alaska, 2004-2023.

Victoria A Balta1,2, Sara Bressler1, Stephanie Massay3

  • 1Arctic Investigations Program, Division of Infectious Disease Readiness and Innovation, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Anchorage, Alaska, USA.

The Journal of Infectious Diseases
|March 4, 2025
PubMed
Summary
This summary is machine-generated.

Invasive group B streptococcal (GBS) disease is increasing in non-pregnant Alaska adults. Older adults and those with diabetes face the highest risk, necessitating increased provider awareness for timely treatment.

Keywords:
Streptococcus agalactiaeAlaskaadultincidencepublic healthsurveillance

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Area of Science:

  • Epidemiology
  • Infectious Diseases
  • Public Health

Background:

  • Group B Streptococcus (GBS) is a significant cause of invasive disease.
  • Understanding GBS epidemiology in non-pregnant adults is crucial for public health strategies.
  • Alaska presents a unique demographic for studying GBS trends.

Purpose of the Study:

  • To describe the epidemiology of invasive GBS disease among non-pregnant adults in Alaska.
  • To identify trends in incidence and risk factors for invasive GBS disease.
  • To inform healthcare providers about at-risk populations.

Main Methods:

  • Utilized statewide surveillance data from Alaska.
  • Analyzed cases of invasive GBS disease reported between 2004 and 2023.
  • Calculated age-adjusted annual incidence rates and incidence rate ratios.

Main Results:

  • Reported 880 cases of invasive GBS disease over the study period.
  • Observed a 1.9-fold increase in incidence between 2004-2013 and 2014-2023.
  • Identified adults aged ≥65 years (4.4-fold higher risk) and those with diabetes (47% of cases) as high-risk groups.

Conclusions:

  • Invasive GBS disease incidence is rising in non-pregnant Alaska adults.
  • Older adults and individuals with diabetes are disproportionately affected.
  • Enhanced awareness among healthcare providers is recommended for prompt diagnosis and treatment.