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Related Concept Videos

Neural Regulation01:37

Neural Regulation

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Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
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Related Experiment Video

Updated: May 5, 2026

Electroconvulsive Seizures in Rats and Fractionation of Their Hippocampi to Examine Seizure-induced Changes in Postsynaptic Density Proteins
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Sacral Neuromodulation in Multiple Sclerosis: The NEMISIS Study.

Harry J Kendall1, Armelle Knops1, Oliver Gerlach2

  • 1Department of Urology, Maastricht University Medical Center +, Maastricht, The Netherlands.

European Urology Focus
|March 4, 2025
PubMed
Summary
This summary is machine-generated.

Sacral neuromodulation (SNM) shows promise for neurogenic overactive bladder in multiple sclerosis patients. A multicentre trial will begin in 2025 to confirm SNM

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Area of Science:

  • Urology
  • Neurology
  • Medical Devices

Background:

  • Neurogenic overactive bladder (OAB) is a common complication of multiple sclerosis (MS).
  • Current treatments for MS-related neurogenic OAB have limitations.
  • Sacral neuromodulation (SNM) has emerged as a potential therapeutic option.

Purpose of the Study:

  • To evaluate the therapeutic benefit of sacral neuromodulation (SNM) for neurogenic overactive bladder (OAB) in patients with multiple sclerosis (MS).

Main Methods:

  • A multicentre, randomised controlled trial is planned.
  • Patient recruitment is scheduled to commence in the first half of 2025.

Main Results:

  • This section is not applicable for the current abstract as the study has not yet commenced.

Conclusions:

  • Further research is warranted to establish the efficacy of SNM in this patient population.