A Novel Pipeline for Adrenal Gland Segmentation: Integration of a Hybrid Post-Processing Technique with Deep Learning

Accurate segmentation of adrenal glands from CT images is essential for enhancing computer-aided diagnosis and surgical planning. However, the small size, irregular shape, and proximity to surrounding tissues make this task highly challenging. This study introduces a novel pipeline that significantly improves the segmentation of left and right adrenal glands by integrating advanced pre-processing techniques and a robust post-processing framework. Utilising a 2D UNet architecture with various backbones (VGG16, ResNet34, InceptionV3), the pipeline leverages test-time augmentation (TTA) and targeted removal of unconnected regions to enhance accuracy and robustness. Our results demonstrate a substantial improvement, with a 38% increase in the Dice similarity coefficient for the left adrenal gland and an 11% increase for the right adrenal gland on the AMOS dataset, achieved by the InceptionV3 model. Additionally, the pipeline significantly reduces false positives, underscoring its potential for clinical applications and its superiority over existing methods. These advancements make our approach a crucial contribution to the field of medical image segmentation.