Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hyperglycemia01:29

Hyperglycemia

25
Hyperglycemia is an abnormally high blood glucose level. It is diagnosed by fasting glucose ≥126 mg/dL, 2-hour oral glucose tolerance test (or OGTT) ≥200 mg/dL, random glucose ≥200 mg/dL with symptoms, or HbA1c ≥6.5%. However, HbA1c results may be unreliable in certain conditions, such as anemia or hemoglobinopathies, and the diagnosis should be confirmed unless classic symptoms are present. Postprandial hyperglycemia is typically considered significant when glucose...
25

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Quantifying expert resistance perception from vessel wall deformation in intracranial catheter navigation.

Journal of neurointerventional surgery·2026
Same author

Traction Cybernetic Avatar System for Colon ESD.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025
Same author

Measurement of lactate concentration using a minimally invasive needle with non-planer optical waveguides.

Biosensors & bioelectronics·2025
Same author

Persistently High Platelet Factor 4 Levels in an Adolescent with Recurrent Late Thrombotic Complications after SARS-CoV-2 mRNA Vaccination.

Hematology reports·2024
Same author

Automatic irrigation system with a fiber-optic pressure sensor regulating intrapelvic pressure for flexible ureteroscopy.

Scientific reports·2023
Same author

Development of modified laser Doppler flowmetry device for real-time monitoring of esophageal mucosal blood flow: a preclinical assessment with an animal model.

Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs·2023

Related Experiment Video

Updated: May 1, 2026

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing
08:19

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing

Published on: June 1, 2012

14.3K

Minimally Invasive Needle for Local Glucose Tolerance Tests in Skin.

Noriko Tsuruoka, Yoichi Haga

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
    |March 5, 2025
    PubMed
    Summary

    Researchers developed a minimally invasive needle to measure insulin resistance, a key factor in type 2 diabetes. This device allows for local glucose tolerance tests directly in the skin, aiding diabetes management.

    More Related Videos

    Studying the Hypothalamic Insulin Signal to Peripheral Glucose Intolerance with a Continuous Drug Infusion System into the Mouse Brain
    08:32

    Studying the Hypothalamic Insulin Signal to Peripheral Glucose Intolerance with a Continuous Drug Infusion System into the Mouse Brain

    Published on: January 4, 2018

    10.2K
    Human Subcutaneous Adipose Tissue Sampling Using a Mini-Liposuction Technique
    08:59

    Human Subcutaneous Adipose Tissue Sampling Using a Mini-Liposuction Technique

    Published on: September 27, 2021

    2.9K

    Related Experiment Videos

    Last Updated: May 1, 2026

    Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing
    08:19

    Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing

    Published on: June 1, 2012

    14.3K
    Studying the Hypothalamic Insulin Signal to Peripheral Glucose Intolerance with a Continuous Drug Infusion System into the Mouse Brain
    08:32

    Studying the Hypothalamic Insulin Signal to Peripheral Glucose Intolerance with a Continuous Drug Infusion System into the Mouse Brain

    Published on: January 4, 2018

    10.2K
    Human Subcutaneous Adipose Tissue Sampling Using a Mini-Liposuction Technique
    08:59

    Human Subcutaneous Adipose Tissue Sampling Using a Mini-Liposuction Technique

    Published on: September 27, 2021

    2.9K

    Area of Science:

    • Biomedical Engineering
    • Endocrinology
    • Diabetes Research

    Background:

    • Type 2 diabetes is characterized by impaired insulin secretion and insulin resistance.
    • Accurate assessment of these abnormalities is crucial for diabetes diagnosis, management, and prevention.
    • Current methods for measuring insulin resistance can be invasive or complex.

    Purpose of the Study:

    • To develop and evaluate a minimally invasive device for measuring insulin resistance.
    • To enable local glucose tolerance tests for improved diabetes assessment.
    • To assess the functionality of a novel needle for glucose administration and measurement in skin tissue.

    Main Methods:

    • Fabrication of a minimally invasive needle with integrated measurement and administration channels.
    • Insertion of the needle into mouse skin for local glucose tolerance testing.
    • Administration of glucose via the needle's channel and measurement of skin glucose concentration using microperfusion before and after administration.
    • Evaluation of the needle's glucose administration and collection capabilities in vivo.

    Main Results:

    • Successful fabrication of a functional minimally invasive needle device.
    • Demonstration of glucose administration and subsequent glucose concentration measurement within the skin tissue.
    • Validation of the needle's dual function for both administering and collecting samples for local glucose tolerance tests.
    • The device showed promising performance in preliminary evaluations on mouse skin.

    Conclusions:

    • A novel, minimally invasive needle system has been developed for assessing insulin resistance.
    • This device facilitates local glucose tolerance testing, offering a potentially more efficient and less invasive method for diabetes evaluation.
    • Further research and development could lead to improved clinical tools for diabetes management and prevention strategies.