Related Experiment Video

Updated: Jul 25, 2026

Dorsal Column Steerability with Dual Parallel Leads using Dedicated Power Sources: A Computational Model
11:19

Dorsal Column Steerability with Dual Parallel Leads using Dedicated Power Sources: A Computational Model

Published on: February 10, 2011

11.8K

Computational Modeling of Dorsal Root Ganglion Stimulation: Understanding Pain Suppression Mechanisms

Sajjad Rigi Ladez, Jia Liu, Longtu Chen

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
    |March 5, 2025
    PubMed

    More Related Videos

    Author Spotlight: In Vitro and In Vivo Models to Enhance Chronic Pain Treatment Efficacy06:56

    Author Spotlight: In Vitro and In Vivo Models to Enhance Chronic Pain Treatment Efficacy

    Published on: June 28, 2024

    816
    In Vivo Thoracic Dorsal Root Ganglia (DRG) Calcium Imaging and ECG Recording for Studying Peripheral Nerve Stimulation06:34

    In Vivo Thoracic Dorsal Root Ganglia (DRG) Calcium Imaging and ECG Recording for Studying Peripheral Nerve Stimulation

    Published on: August 16, 2024

    690

    Related Concept Videos

    Nociception01:44

    Nociception

    Nociception—the ability to feel pain—is essential for an organism’s survival and overall well-being. Noxious stimuli such as piercing pain from a sharp object, heat from an open flame, or contact with corrosive chemicals are first detected by sensory receptors, called nociceptors, located on nerve endings. Nociceptors express ion channels that convert noxious stimuli into electrical signals. When these signals reach the brain via sensory neurons, they are perceived as pain. Thus, pain helps the...
    Blood and Nerve Supply to the Bones01:29

    Blood and Nerve Supply to the Bones

    Bones are dynamic organs that require a rich supply of oxygen and nutrients. Around 5% to 10% of the cardiac output supplies blood to the bones. A typical long bone has three main sources: the nutrient artery, the metaphyseal and epiphyseal arteries, and the periosteal arteries.
    Nutrient Artery
    The nutrient artery is the main blood vessel that enters the diaphysis via the nutrient foramen. While most long bones have only one nutrient foramen, large bones, such as the femur, may have two. This...
    Analgesia and Pain Management01:25

    Analgesia and Pain Management

    Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
    Pain01:20

    Pain

    Pain serves as a critical warning signal that alerts the body to potential or actual harm. When mechanical pressure on the skin is intense, such as from a sharp pinch, the sensation transitions from touch to pain. Similarly, extreme temperatures, like a hot pot handle, convert the sensation of heat into pain. Pain can also result from overstimulation of other senses, such as blinding light, loud noise, or the intense heat from habañero peppers. This ability to sense pain is essential for...