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Updated: Jun 25, 2026

Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation
Published on: July 16, 2014
A Compact Dead-Zone-Free Multi-Channel Stimulation and Recording System for Precision Peripheral Nerve Modulation
Abstract:
Peripheral nerve modulation has a certain potential in motor recovery, but the majority of systems suffer from the drawback of dead time caused by switching channels to achieve multi-channel stimulation. As a response to this challenge, we have developed a peripheral nerve modulation device with 64-channel recording and 16-channel stimulation without dead time. Through modulation of the rat sciatic nerve, we identified the crucial role of initial phase and amplitude in the outcomes of dual-channel combined stimulation. This design not only enhanced neural activation capabilities with constant power supply but also achieves more precise neural activation and reduces unintentional activation.

