Wireless Mouse EEG Device: Novel Design for Easy Operation

Electroencephalogram (EEG) has been widely used in studies using rodent models to understand brain functions and neurological disorders. However, conventional EEG setups have limits as recording devices are bulky and tethered, causing discomfort and deviating from natural habitat conditions. To address these, we develop an innovative wireless EEG device for mice with a compact size, wireless recording via Bluetooth, and minimal invasiveness through screw mounting. The device enhances experimental setups while ensuring the well-being of the mice in a more realistic environment facilitating easier translation to human studies. In an experimental setting involving induced seizures, EEG signals were recorded and analyzed to discern differences across epilepsy phases in both anesthetized and awake stages. This device holds promise to revolutionize EEG research using mice, bridging the gap between laboratory conditions and real-world scenarios, thus advancing our understanding of neurological phenomena.