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Coarctation of the aorta and persistent left superior vena cava: HDlive Flow features at 14 weeks of gestation

Toshiyuki Hata1,2, Aya Koyanagi1, Riko Takayoshi1,2

  • 1Department of Obstetrics and Gynaecology, Miyake Clinic, Okayama, Japan.

Case Reports in Perinatal Medicine
|March 5, 2025
PubMed

Insights

This study reports the first prenatal diagnosis of coarctation of the aorta (CoA) and persistent left superior vena cava (PLSVC) using HDlive Flow and STIC at 14 weeks gestation.

Area of Science:

  • Fetal cardiology
  • Medical imaging
  • Prenatal diagnosis

Background:

  • Coarctation of the aorta (CoA) diagnosis relies on identifying discrepancies between the ductus arteriosus and aorta.
  • Persistent left superior vena cava (PLSVC) is a known associated anomaly.
  • Previous HDlive Flow imaging for these conditions was limited to the third trimester.

Observation:

  • A case of fetal CoA and PLSVC was identified at 14 weeks gestation using trans-abdominal ultrasound.
  • HDlive Flow with spatiotemporal image correlation (STIC) visualized key anatomical features, including PLSVC and aortic isthmus narrowing.
  • Neonatal echocardiography confirmed the prenatal diagnosis.

Findings:

  • HDlive Flow with STIC enabled early second-trimester detection of fetal CoA and PLSVC.
  • The technique clearly delineated spatial relationships between great vessels and identified suspected preductal shelf.
  • This represents the earliest reported prenatal visualization of these combined anomalies.

Implications:

  • Early prenatal diagnosis of CoA and PLSVC is possible using advanced ultrasound techniques.
  • This may improve prenatal counseling and planning for affected neonates.
  • Further research can explore the utility of HDlive Flow in earlier gestational age assessments.
Abstract

Keywords:
HDlive Flowcoarctation of aortaearly second trimesterpersistent left superior vena cavaprenatal diagnosisspatiotemporal image correlation (STIC)

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