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Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis

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Chinese Position Paper on Biologic Therapy for Chronic Rhinosinusitis With Nasal Polyps.

Mu Xian^1,2,3, Bing Yan^1,2,3, Xicheng Song⁴

¹Department of Otolaryngology, Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University, Beijing, China.

|March 5, 2025

Summary

Biologic agents offer new hope for severe chronic rhinosinusitis with nasal polyps (CRSwNP). This expert consensus provides guidance for their use in China, standardizing treatment for better patient outcomes.

Keywords:

China biologics chronic rhinosinusitis with nasal polyps monoclonal antibody treatment

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Area of Science:

Otolaryngology
Immunology
Pharmacology

Background:

Severe chronic rhinosinusitis with nasal polyps (CRSwNP) presents challenges in China.
Biologics targeting cytokines offer a promising therapeutic avenue for CRSwNP.
Rapid advancements in biologic therapies are occurring in China.

Framework:

An expert panel convened to establish consensus on biologic agent application for CRSwNP in China.
The panel comprised principal investigators experienced in CRSwNP biologic clinical trials.
Discussions focused on CRSwNP pathogenesis, biologic mechanisms, and clinical evidence.

Implementation:

Reviewed latest research, emphasizing Chinese clinical trial data.
Addressed efficacy and safety of biologic treatments for CRSwNP.
Focused on a Chinese perspective for biologic agent application.

Implications:

Developed consensus on prescription criteria, treatment duration, and efficacy evaluation for CRSwNP biologics in China.
Aims to guide Chinese physicians in utilizing biologic agents for CRSwNP.
This position paper will be updated as clinical experience with biologics grows.