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[The microbiome and the first 1,000 days of life]
1Preventive Dentistry, Academic Centre for Dentistry Amsterdam, the Netherlands.
Insights
The first 1,000 days of life are critical for establishing a healthy human microbiome. Factors from prenatal development through the postnatal period significantly shape this vital microbial community.
Area of Science:
- Microbiology
- Immunology
- Developmental Biology
Abstract:
A healthy human being lives in symbiosis with his microbes or microbiome. The first 1,000 days of life are crucial for developing a healthy and diverse microbiome. The development of a healthy microbiome begins as early as in the womb, where the training of the fetal immune cells begins. Next, the child s microbiome is influenced by the method of delivery during the birthing process. The largest and most important phase is the postnatal period. In this last phase, the child s environment, the behaviour and lifestyle of its caregivers, and the child itself are the main determinants of developing and maintaining a healthy microbiome.
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